CYP2R1 抗体 (AA 251-350) (Alexa Fluor 647)
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- 抗原 See all CYP2R1 抗体
- CYP2R1 (Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))
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抗原表位
- AA 251-350
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CYP2R1 antibody is conjugated to Alexa Fluor 647
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠
- 预测反应
- Rat,Dog,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CYP2R1
- 亚型
- IgG
- Top Product
- Discover our top product CYP2R1 Primary Antibody
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anti-Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1) (Internal Region) antibody
CYP2R1 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1) (AA 152-180) antibodyCYP2R1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB15785 unconjugated
anti-Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1) (Internal Region) antibodyCYP2R1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1) (Internal Region) antibodyCYP2R1 适用: 人, 小鼠, 猴 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1) (AA 1-501) antibodyCYP2R1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1) (AA 1-501) antibodyCYP2R1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1) (AA 405-418) antibodyVerified CYP2R1 适用: 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1) (AA 179-228) antibodyCYP2R1 适用: 人, 小鼠, 大鼠, 猴, Pig, 犬, 马, 斑马鱼, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1) (AA 252-501) antibodyCYP2R1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1) (AA 464-496), (C-Term) antibodyCYP2R1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB17016 unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- CYP2R1 (Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))
- 别名
- CYP2R1 (CYP2R1 产品)
- 别名
- cytochrome P450 family 2 subfamily R member 1 antibody, cytochrome P450, family 2, subfamily R, polypeptide 1 antibody, cytochrome P450, family 2, subfamily r, polypeptide 1 antibody, CYP2R1 antibody, cyp2r1 antibody, Cyp2r1 antibody
- 背景
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Synonyms: Cytochrome P450 2R1, Cytochrome P450 family 2 R1, Cytochrome P450 family 2 subfamily R polypeptide 1, EC 1.14.13.15, MGC4663, Vitamin D 25 hydroxylase.
Background: CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are mono-oxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor.Defects in CYP2R1 are a cause of 25-hydroxyvitamin D(3) deficiency, also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency. First described in patients who had rickets at a young age despite a history of adequate vitamin D intake. The patients sera had low calcium concentrations, low phosphate concentrations, elevated alkaline phosphatase activity and low levels of 25-hydroxyvitamin D.
- 基因ID
- 120227
- 途径
- Metabolism of Steroid Hormones and Vitamin D
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