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GM1123 抗体 (AA 21-120) (Alexa Fluor 488)

GM1123 适用: 人, 小鼠, 大鼠 WB, FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 488
产品编号 ABIN892070
发货至: 中国
  • 抗原 See all GM1123 products
    GM1123 (Predicted Gene 1123 (GM1123))
    抗原表位
    AA 21-120
    适用
    • 19
    • 19
    • 19
    • 4
    • 4
    • 4
    人, 小鼠, 大鼠
    宿主
    • 19
    克隆类型
    • 19
    多克隆
    标记
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GM1123 antibody is conjugated to Alexa Fluor 488
    应用范围
    • 19
    • 17
    • 12
    • 12
    • 3
    • 3
    • 3
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Cow,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Coxsackie Adenovirus Receptor
    亚型
    IgG
  • 应用备注
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    GM1123 (Predicted Gene 1123 (GM1123))
    别名
    Coxsackie Adenovirus Receptor (GM1123 产品)
    别名
    AV052824 antibody, CLSP antibody, predicted gene 1123 antibody, coxsackie virus and adenovirus receptor-like 1-like antibody, Gm1123 antibody, LOC100359797 antibody
    背景

    Synonyms: CAR, HCAR, CAR4/6, Coxsackievirus and adenovirus receptor, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, HCVADR, CXADR

    Background: Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.

    基因ID
    1525
    UniProt
    P78310
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