Keratin 12 (KRT12) 抗体 (Alexa Fluor 647)

ABIN890816 产品详细信息, 供应商: Log in to see
抗原
  • fb05e09
  • wu:fa91b04
  • wu:fa97a07
  • wu:fb05e09
  • k12
  • xk81b2
  • K12
  • AI835216
  • Krt-12
  • Krt1-12
  • Ka12
  • keratin 91
  • keratin 12
  • keratin 12 S homeolog
  • krt91
  • KRT12
  • krt12
  • Krt12
  • krt12.S
适用
人, 小鼠, 大鼠
55
26
25
2
1
宿主

59
4
1
克隆类型
多克隆
标记
Alexa Fluor 647
6
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
应用范围
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
45
29
22
16
12
11
3
2
2
1
1
1
选项
Supplier
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免疫原 KLH conjugated synthetic peptide derived from human CK12/Cytokeratin 12
亚型 IgG
纯化方法 Purified by Protein A.
抗原 Keratin 12 (KRT12)
别名 CK12 (KRT12 Antibody 摘要)
背景

Cytokeratin 12 is a member of the intermediate filament family of proteins and is a heterotetramer of two type I and two type II keratins. Keratin 3 is specifically expressed in the corneal epithelium with family member KRT12. Cytokeratin 12 encodes the type I intermediate filament chain keratin 12, expressed in corneal epithelia. Defects in KRT3 and KRT12 are a cause of Meesmann corneal dystrophy (MCD), an autosomal dominant disease that causes fragility of the anterior corneal epithelium. Symptoms occur in adulthood and include rupture of the corneal microcysts that may lead to photophobia, contact lens intolerance and intermittent diminution of visual acuity. Defects in KRT12 are a cause of juvenile epithelial corneal dystrophy of Meesmann (MCD)

Synonyms: 65 kDa cytokeratin, CK 12, CK 3, CK12, CK3, Cytokeratin 12, Cytokeratin 3, K12, K3, keratin 12 Meesmann corneal dystrophy, Keratin 12, Keratin 3, Keratin, type I cytoskeletal 12, K1C12_HUMAN, Keratin, type II cytoskeletal 3, KRT12, KRT3.

分子量 54kDa
基因ID 3859
应用备注 IF(IHC-P) 1:50-200
限制 仅限研究用
状态 Liquid
浓度 1 μg/μL
缓冲液 Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
储存条件 4 °C
储存方法 Store at 4°C
有效期 12 months