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PKC zeta 抗体 (pThr410) (AbBy Fluor® 488)

This anti-PKC zeta antibody is a 兔 多克隆 antibody detecting PKC zeta in WB, IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN878195
发货至: 中国

Quick Overview for PKC zeta 抗体 (pThr410) (AbBy Fluor® 488) (ABIN878195)

抗原

See all PKC zeta (PRKCZ) 抗体
PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))

适用

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宿主

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克隆类型

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多克隆

标记

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This PKC zeta antibody is conjugated to AbBy Fluor® 488

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
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    pThr410

    预测反应

    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human PRKCZ around the phosphorylation site of Thr410

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))

    别名

    PRKCZ

    背景

    Synonyms: PRKCZphospho T410, PRKCZphospho Thr410, p-PRKCZT410, rotein Kinase C, AAG6, Aging associated gene 6, MGC129900, MGC129901, MGC41878, MGC57564, PKC B, PKC beta, PKC zeta, PKC2, PKCB, PKCC, PKCD, PKCE, PKCG, PRKACA, PRKC A, PRKC G, PRKCA, PRKCB, PRKCB1, PRKCB2, PRKCD, PRKCE, PRKCG, PRKCZ , Protein kinase C alpha, Protein kinase C alpha type, Protein Kinase C, Protein kinase C beta 1, Protein kinase C beta 1 polypeptide, Protein kinase C beta, Protein kinase C beta type, Protein kinase C delta, Protein kinase C epsilon, Protein kinase C gamma, Protein kinase C gamma type, Protein kinase C zeta, SCA14, Spinocerebellar ataxia 14.

    Background: Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

    基因ID

    5590

    途径

    NF-kappaB Signaling, RTK signaling, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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