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TNF alpha 抗体

Name: TNF alpha 抗体
SKU: ABIN872451
Availability: OutOfStock

This anti-TNF alpha antibody is a 兔多克隆 antibody detecting TNF alpha in WB, IHC (p) 和 IF (p). Suitable for 人, Pig 和犬. This Primary Antibody has been cited in 2+ publications.

Formalin-fixed and paraffin embedded human lung labeled with Anti-TNF-alpha Polyclonal Antibody, Unconjugated (ABIN872451) at 1:200 followed by conjugation to the secondary antibody and DAB staining (TNF alpha 抗体)

IHC

1 image

(2 references)

产品编号 ABIN872451

发货至: 中国

Quick Overview for TNF alpha 抗体 (ABIN872451)

抗原

See all TNF alpha 抗体

TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

适用

人, Pig, 犬

宿主

兔

克隆类型

多克隆

标记

This TNF alpha antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Discover our top product TNF alpha Primary Antibody

交叉反应

犬, 人, Pig

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from dog TNF-alpha

亚型

IgG
anti-Tumor Necrosis Factor alpha (TNF alpha) (AA 181-235) antibody
TNF alpha 适用: 人, 小鼠, 大鼠, 兔, 马 WB, ELISA, IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Tumor Necrosis Factor alpha (TNF alpha) antibody
TNF alpha 适用: 人, 大鼠 IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal TNFA-1172 unconjugated

anti-Tumor Necrosis Factor alpha (TNF alpha) (AA 77-233) antibody
TNF alpha 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Tumor Necrosis Factor alpha (TNF alpha) (AA 1-233) antibody
TNF alpha 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal M1-C4 unconjugated

anti-Tumor Necrosis Factor alpha (TNF alpha) antibody (FITC)
TNF alpha 适用: 人, Pig, Non-Human Primate ICFC 宿主: 小鼠 Monoclonal MAb11 FITC

anti-Tumor Necrosis Factor alpha (TNF alpha) (AA 80-227) antibody
TNF alpha 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Tumor Necrosis Factor alpha (TNF alpha) (AA 86-150) antibody
TNF alpha 适用: 人, 小鼠, 大鼠, Pig, 兔 WB, ELISA, IHC (p), IF (p), IHC (fro), IF (cc) 宿主: 兔 Polyclonal unconjugated

anti-Tumor Necrosis Factor alpha (TNF alpha) antibody
TNF alpha 适用: 人, 小鼠 WB, IHC (p), IF (p) 宿主: 小鼠 Monoclonal 1F6 unconjugated

anti-Tumor Necrosis Factor alpha (TNF alpha) (AA 80-235) antibody
TNF alpha 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Necrosis Factor alpha (TNF alpha) (AA 80-235) antibody
TNF alpha 适用: 小鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated

应用备注

WB (1:100-500),IHC-P (1:100-500),IF (p) (1:100-500)

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C for 12 months.

有效期

12 months
Zhang, Liu, Hu, Jiang, Zhu: ""Proof-of-principle" concept for ultrasensitive detection of cytokines based on the electrically heated carbon paste electrode." in: Chemical communications (Cambridge, England), Vol. 47, Issue 23, pp. 6551-3, (2011) (PubMed).

Liao, Zhou, Ji, Zhang: "Eccentric contraction induces inflammatory responses in rat skeletal muscle: role of tumor necrosis factor-alpha." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 298, Issue 3, pp. R599-607, (2010) (PubMed).
抗原

TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

别名

TNF-alpha

背景

Synonyms: APC1, Cachectin, D, Dferentiation inducing factor, Macrophage cytotoxic factor, MCF, Necrosin, TNF a, TNF alpha, TNF, TNF Macrophage Derived, TNF Monocyte Derived, TNF Superfamily Member 2, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2, Tumor Necrosis Factor Precursor, Tumour Necrosis Factor Alpha, TNFA_HUMAN.
Background: Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide stimulated macrophages, and causes tumor necrosis when injected into tumour bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS PAGE under non reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumour Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.

分子量

17/26kDa

基因ID

403922

途径

NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome