SRRT 抗体 (AA 721-800)
Quick Overview for SRRT 抗体 (AA 721-800) (ABIN872317)
抗原
See all SRRT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 721-800
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Cow,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ARS2
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亚型
- IgG
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anti-Serrate RNA Effector Molecule Homolog (SRRT) (AA 1-796) antibody
SRRT 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Serrate RNA Effector Molecule Homolog (SRRT) (C-Term) antibodyVerified SRRT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Serrate RNA Effector Molecule Homolog (SRRT) (AA 627-876) antibodySRRT 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Serrate RNA Effector Molecule Homolog (SRRT) (AA 733-766) antibodySRRT 适用: 人, 斑马鱼 WB 宿主: 兔 Polyclonal RB53167 unconjugated
anti-Serrate RNA Effector Molecule Homolog (SRRT) (AA 878-910) antibodySRRT 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53166 unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- SRRT (Serrate RNA Effector Molecule Homolog (SRRT))
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别名
- ARS2
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背景
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Synonyms: ARS2 protein, Arsenate resistance protein ARS2, Arsenite resistance protein 2, Arsenite resistance protein, ASR2, MGC126427, Serrate, Serrate RNA effector molecule homolog Arabidopsis, Serrate RNA effector molecule homolog, SRRT, SRRT_HUMAN.
Background: ARS2(Arsenite resistance protein 2) confers arsenite resistance. The protein belongs to the ARS2 family. Arsenic is a human carcinogen whose mechanism of action is unknown. The arsenite acts as a comutagen by interfering with DNA repair. Two genes, ASR1(Arsenite resistance protein 1) and ASR2 (Arsenite resistance protein 2), confer arsenite resistance to arsenite-sensitive cells. ASR1 shows almost complete homology with the rat fau gene, a tumor suppressor gene which contains a ubiquitin like region fused to S30 ribosomal protein. Arsenite inhibits ubiquitin dependent proteolysis. The tumor suppressor fau gene product or some other aspect of the ubiquitin system may be a target for arsenic toxicity and that disruption of the ubiquitin system may contribute to the genotoxicity and carcinogenicity of arsenite.
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基因ID
- 51593
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途径
- Notch Signaling, Stem Cell Maintenance
抗原
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