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SRRT 抗体 (AA 627-876)

SRRT 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7169355
发货至: 中国
  • 抗原 See all SRRT 抗体
    SRRT (Serrate RNA Effector Molecule Homolog (SRRT))
    抗原表位
    • 8
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 627-876
    适用
    • 25
    • 7
    • 5
    • 1
    宿主
    • 23
    • 2
    • 1
    克隆类型
    • 26
    多克隆
    标记
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    This SRRT antibody is un-conjugated
    应用范围
    • 23
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Serrate RNA effector molecule homolog protein (627-876AA)
    亚型
    IgG
    Top Product
    Discover our top product SRRT Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SRRT (Serrate RNA Effector Molecule Homolog (SRRT))
    别名
    SRRT (SRRT 产品)
    别名
    CG7843 antibody, Dmel\\CG7843 antibody, anon-WO0118547.166 antibody, ars2 antibody, ars2-A antibody, serrate antibody, ARS2 antibody, ASR2 antibody, 2810019G02Rik antibody, ASR2A antibody, ASR2B antibody, ASR2C antibody, ASR2D antibody, Ars2 antibody, Asr2 antibody, MGC92060 antibody, CHUNP6881 antibody, zgc:92060 antibody, Arsenic resistance protein 2 antibody, serrate, RNA effector molecule S homeolog antibody, serrate, RNA effector molecule antibody, serrate RNA effector molecule homolog (Arabidopsis) antibody, Ars2 antibody, srrt.S antibody, SRRT antibody, Srrt antibody, srrt antibody
    背景

    Background: Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA), however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity).

    Aliases: ARS2 protein antibody, Arsenate resistance protein ARS2 antibody, Arsenite resistance protein 2 antibody, Arsenite resistance protein antibody, Arsenite-resistance protein 2 antibody, ASR2 antibody, MGC126427 antibody, Serrate antibody, Serrate RNA effector molecule antibody, Serrate RNA effector molecule homolog (Arabidopsis) antibody, Serrate RNA effector molecule homolog antibody, SRRT antibody, SRRT_HUMAN antibody

    UniProt
    Q9BXP5
    途径
    Notch Signaling, Stem Cell Maintenance
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