RING1 抗体 (AA 35-39)
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- 抗原 See all RING1 抗体
- RING1 (Ring Finger Protein 1 (RING1))
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抗原表位
- AA 35-39
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RING1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- The antibody detects endogenous level of total Ring1A protein.
- 纯化方法
- Affinity purified
- 免疫原
- Peptide sequence around AA 35-39 ( I-A-V-S-P) derived from Human Ring1A. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- Top Product
- Discover our top product RING1 Primary Antibody
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anti-Ring Finger Protein 1 (RING1) (AA 79-263) antibody
RING1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 8C12F4 unconjugated
anti-Ring Finger Protein 1 (RING1) antibodyRING1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 79-263) antibodyRING1 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 8E8A2 unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 81-170) antibodyRING1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B3 unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 81-170) antibodyRING1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4E8 unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 401-630) antibodyRING1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 281-392) antibodyRING1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 1 (RING1) antibodyRING1 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 81-170) antibodyRING1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein 1 (RING1) (AA 81-170) antibodyRING1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A6 unconjugated
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- 应用备注
- Western blotting: 1:500-1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- 抗原
- RING1 (Ring Finger Protein 1 (RING1))
- 别名
- Ring1A (RING1 产品)
- 别名
- RING1A antibody, RNF1 antibody, Ring1A antibody, bap-1 antibody, bap1 antibody, ding antibody, hipi3 antibody, ring1a antibody, ring1b antibody, ring2 antibody, rnf1 antibody, rnf2-a antibody, ring1 antibody, ring1b-B antibody, rnf2-b antibody, ring finger protein 1 antibody, ring finger protein 1 S homeolog antibody, ring finger protein 1 L homeolog antibody, RING1 antibody, Ring1 antibody, ring1.S antibody, ring1.L antibody
- 背景
- Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex act via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. Compared to RNF2/RING2, it does not have the main E3 ubiquitin ligase activity on histone H2A, and it may rather act as a modulator of RNF2/RING2 activity.
- 分子量
- 58 kDa
- 基因ID
- 6015
- NCBI登录号
- NP_002922
- UniProt
- Q06587
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