GABRA3 抗体 (AA 33-37)
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- 抗原 See all GABRA3 抗体
- GABRA3 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3))
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抗原表位
- AA 33-37
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GABRA3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- The antibody detects endogenous level of total GABA A Receptor a3 protein.
- 纯化方法
- Affinity purified
- 免疫原
- Peptide sequence around AA 33-37 (R-R-Q-E-P) derived from Rat GABA A Receptor a3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- Top Product
- Discover our top product GABRA3 Primary Antibody
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anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) antibody
GABRA3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) antibodyGABRA3 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) (N-Term) antibodyGABRA3 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) (AA 29-43) antibodyGABRA3 适用: 大鼠, 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) (AA 480-492) antibodyGABRA3 适用: 人, 大鼠, 小鼠, Cow, 兔, 马, 猴, Bat, Hamster IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) (C-Term) antibodyGABRA3 适用: 人, 兔, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) (N-Term) antibodyGABRA3 适用: 人, 大鼠, 小鼠, 犬, Cow, 兔, 马, 猴, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) (Middle Region) antibodyGABRA3 适用: 人, 大鼠, 小鼠, 犬, Cow, 兔, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) (AA 29-43), (Extracellular), (N-Term) antibodyGABRA3 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, IF, IP, LCI 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) antibodyGABRA3 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Western blotting: 1:500-1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- 抗原
- GABRA3 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3))
- Abstract
- GABRA3 产品
- 别名
- GABRA3 antibody, Gabra-3 antibody, si:ch211-113k9.1 antibody, gamma-aminobutyric acid type A receptor alpha3 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, alpha 3 antibody, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3 antibody, gamma-aminobutyric acid receptor subunit alpha-3 antibody, GABRA3 antibody, gabra3 antibody, Gabra3 antibody, LOC100653496 antibody
- 背景
- GABA (g-aminobutyric acid) is the primary inhibitory neurotransmitter in the central nervous system and interacts with three different receptors: GABA(A), GABA(B) and GABA(C) receptor. The ionotropic GABA(A) and GABA(C) receptors are ligand-gated ion channels that produce fast inhibitory synaptic transmission. In contrast, the metabotropic GABA(B) receptor is coupled to G proteins that modulate slow inhibitory synaptic transmission (1). Functional GABA(B) receptors form heterodimers of GABA(B)R1 and GABA(B)R2 where GABA(B)R1 binds the ligand and GABA(B)R2 is the primary G protein contact site (2). Two isoforms of GABA(B)R1 have been cloned: GABA(B)R1a is a 130 kD protein and GABA(B)R1b is a 95 kD protein (3). G proteins subsequently inhibit adenyl cylase activity and modulate inositol phospholipid hydrolysis. GABA(B) receptors have both pre- and postsynaptic inhibitions: presynaptic GABA(B) receptors inhibit neurotransmitter release through suppression of high threshold calcium channels, while postsynaptic GABA(B) receptors inhibit through coupled activation of inwardly rectifying potassium channels. In addition to synaptic inhibition, GABA(B) receptors may also be involved in hippocampal long-term potentiation, slow wave sleep and muscle relaxation
- 分子量
- 51 kDa
- 基因ID
- 24947
- NCBI登录号
- NP_058765
- UniProt
- P20236
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