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FAS 抗体 (AA 323-327)

FAS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN871645
发货至: 中国
  • 抗原 See all FAS 抗体
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    抗原表位
    • 25
    • 16
    • 16
    • 8
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 323-327
    适用
    • 210
    • 67
    • 62
    • 19
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    宿主
    • 158
    • 86
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    克隆类型
    • 156
    • 96
    • 1
    多克隆
    标记
    • 120
    • 27
    • 25
    • 12
    • 10
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FAS antibody is un-conjugated
    应用范围
    • 163
    • 115
    • 72
    • 64
    • 35
    • 34
    • 30
    • 26
    • 26
    • 20
    • 18
    • 9
    • 8
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    The antibody detects endogenous level of total Fas protein.
    纯化方法
    Affinity purified
    免疫原
    Peptide sequence around AA 323-327 (E-N-S-N-F) derived from human Fas . Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    Top Product
    Discover our top product FAS Primary Antibody
  • 应用备注
    Western blotting: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    别名
    Fas (FAS 产品)
    别名
    ALPS1A antibody, APO-1 antibody, APT1 antibody, CD95 antibody, FAS1 antibody, FASTM antibody, TNFRSF6 antibody, AI196731 antibody, APO1 antibody, TNFR6 antibody, Tnfrsf6 antibody, lpr antibody, Fas cell surface death receptor antibody, Fas (TNF receptor superfamily member 6) antibody, FAS antibody, Fas antibody, fas antibody
    背景
    Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
    分子量
    40-50 kDa
    基因ID
    355
    NCBI登录号
    NP_000034
    UniProt
    P25445
    途径
    p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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