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FAS 抗体 (AA 323-327)

This 兔 多克隆 antibody specifically detects FAS in WB. It exhibits reactivity toward 人.
产品编号 ABIN871645
发货至: 中国
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Quick Overview for FAS 抗体 (AA 323-327) (ABIN871645)

抗原

See all FAS 抗体
FAS (TNF Receptor Superfamily, Member 6 (FAS))

适用

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宿主

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克隆类型

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多克隆

标记

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This FAS antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 25
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    AA 323-327

    特异性

    The antibody detects endogenous level of total Fas protein.

    纯化方法

    Affinity purified

    免疫原

    Peptide sequence around AA 323-327 (E-N-S-N-F) derived from human Fas . Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
  • 应用备注

    Western blotting: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    FAS (TNF Receptor Superfamily, Member 6 (FAS))

    别名

    Fas

    背景

    Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

    分子量

    40-50 kDa

    基因ID

    355

    NCBI登录号

    NP_000034

    UniProt

    P25445

    途径

    p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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