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CHEK2 抗体 (AA 514-518)

The 兔多克隆 anti-CHEK2 antibody is suitable to detect CHEK2 in samples from 人. It has been validated for WB.

产品编号 ABIN871613

发货至: 中国

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Quick Overview for CHEK2 抗体 (AA 514-518) (ABIN871613)

抗原

See all CHEK2 抗体

CHEK2 (Checkpoint Kinase 2 (CHEK2))

适用

人

宿主

兔

克隆类型

多克隆

标记

This CHEK2 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product CHEK2 Primary Antibody

抗原表位
34

26

20

18

17

16

15

15

9

8

8

8

6

4

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 514-518

特异性

The antibody detects endogenous levels of total Chk2 protein.

纯化方法

Affinity purified

免疫原

Peptide sequence around AA 514-518 (Q-P-S-T-S) derived from Chk2 Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
anti-Checkpoint Kinase 2 (CHEK2) (pThr387) antibody
CHEK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (AA 1-543) antibody
CHEK2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4B7 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (AA 1-543) antibody
CHEK2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pThr383) antibody
CHEK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pSer516) antibody
CHEK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pThr68) antibody
CHEK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 适用: 人, 猴, 犬 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 10G7 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 适用: 人, 犬 WB, IHC, IF, IHC (p), IP, FACS 宿主: 小鼠 Monoclonal 5C4 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 适用: 人, 犬 WB, IHC, IHC (p), IP, FACS 宿主: 小鼠 Monoclonal 2H5 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
KD Validated CHEK2 适用: 人 WB, IF (p), FACS 宿主: 兔 Monoclonal 23GB3460 unconjugated Recombinant Antibody

应用备注

Western blotting: 1:500-1:1000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C/-20 °C

储存方法

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
抗原

CHEK2 (Checkpoint Kinase 2 (CHEK2))

别名

Chk2

背景

The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Plays a central role in DNA repair by facilitating cellular response to DNA repair. Required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. Involved in transcriptional regulation of P21 in response to DNA damage. Required for FANCD2 targeting to sites of DNA damage. May function as a transcriptional regulator. Inhibits lipid synthesis by binding to inactive phosphorylated ACACA and preventing its dephosphorylation

分子量

62 kDa

基因ID

11200

NCBI登录号

NP_001005

UniProt

O96017

途径

p53 Pathway, Apoptosis, Cell Division Cycle