CD14 抗体
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北京 101111
Quick Overview for CD14 抗体 (ABIN866061)
抗原
See all CD14 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of CD14.
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交叉反应
- 人, 小鼠
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产品特性
- Positive control: K562 cell lysate. Cellular Localization: Cell membrane
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纯化方法
- Immunogen affinity purified
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亚型
- IgG
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应用备注
- WB: 1:1,000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 1xTBS (pH7.4), 0.5% BSA, 40% Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- CD14
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别名
- CD14
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背景
- CD14 is a glycophosphatidylinositol-anchored protein expressed on the surfaces of monocytes and plymorphonuclear leukocytes. It cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). CD14 acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response and up-regulates cell surface molecules, including adhesion molecules.
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分子量
- 39kDa
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UniProt
- P10810
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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