LKB1 抗体
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北京 101111
Quick Overview for LKB1 抗体 (ABIN865492)
抗原
See all LKB1 (STK11) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human STK11 expressed in E. Coli.
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亚型
- IgG1
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应用备注
- WB: 1/500 - 1/2000, FC: 1/200-1/400, ELISA: Propose dilution 1/10000.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100g/100l
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
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别名
- STK11
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背景
- Essential role in G1 cell cycle arrest. Phosphorylates and activates members of the AMPK-related subfamily of protein kinases. Tumor suppressor.serine/threonine kinase 11,with two alternatively spliced isoforms,expressed in all tissues,strongly homolog of Xenopus early embryonic kinase 1 (XEEK1),tumor suppressor gene in hamartomas syndrome and in left sided colon carcinogenesis,mutated in sporadic testicular cancer,malignant melanomas and laryngeal tumors,playing a minor role in the development of ovarian carcinoma.LKB1 is a potential target for atherosclerosis and cancer and is shown to be mutated in patients with Peutz-Jeghers cancer syndrome. Tissue specificity: Ubiquitously expressed. Strongest expression in testis and fetal liver. Synonyms: PJS, LKB1, STK11
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分子量
- 54kDa
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基因ID
- 6794
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途径
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
抗原
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