MAP2K6 抗体
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北京 101111
Quick Overview for MAP2K6 抗体 (ABIN865464)
抗原
See all MAP2K6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human MAP2K6 expressed in E. Coli.
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亚型
- IgG1
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应用备注
- WB: 1/500 - 1/2000, IHC: 1/200-1/1000, ELISA: Propose dilution 1/10000.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100g/100l
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
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别名
- MAP2K6
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背景
- This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. Tissue specificity: Isoform 2 is only expressed in skeletal muscle. Isoform 1, on the other hand, is found in skeletal muscle, heart, and in lesser extent in liver or pancreas. Synonyms: MEK6, MKK6, MAPKK6, PRKMK6, SAPKK3, MAP2K6
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分子量
- 38kDa
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基因ID
- 5608
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途径
- MAPK Pathway, TLR signaling, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
抗原
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