IGF1R 抗体 (pTyr1165, pTyr1166)
Quick Overview for IGF1R 抗体 (pTyr1165, pTyr1166) (ABIN802233)
抗原
See all IGF1R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr1165, pTyr1166
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Cow,Pig,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human IGF1R around the phosphorylation site of Tyr1165+Tyr1166
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亚型
- IgG
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应用备注
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ELISA 1:500-1000
FCM 1:20-100 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
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别名
- IGF1R +
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背景
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Synonyms: IGF-1R Tyr1165/Tyr1166, IGF1R phospho Y1165+Y1166, IGF1R phospho Tyr1165+Tyr1166, p-IGF1R Tyr1165+Tyr1166, CD221, CD221 antigen, IGF 1 receptor, IGF 1R, IGF I receptor, IGF1R, IGFIR, IGFIRC, Insulin like growth factor 1 receptor, Insulin like growth factor 1 receptor precursor, JTK13, MGC142170, MGC142172, IGF1 Receptor, IGF1R_HUMAN.
Background: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq, Jul 2008].
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基因ID
- 3480
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UniProt
- P08069
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途径
- RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
抗原
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