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GIT1 抗体 (pTyr545) (Cy5.5)

Name: GIT1 抗体 (pTyr545) (Cy5.5)
SKU: ABIN801113
Availability: OutOfStock

This anti-GIT1 antibody is a 兔多克隆 antibody detecting GIT1 in WB, IF (cc) 和 IF (p). Suitable for 人.

产品编号 ABIN801113

发货至: 中国

Quick Overview for GIT1 抗体 (pTyr545) (Cy5.5) (ABIN801113)

抗原

See all GIT1 抗体

GIT1

适用

人

宿主

兔

克隆类型

多克隆

标记

This GIT1 antibody is conjugated to Cy5.5

应用范围

Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Discover our top product GIT1 Primary Antibody

抗原表位
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1

1

1

1

1

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1
pTyr545

预测反应

Human,Mouse,Rat,Cow,Pig

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic phosphopeptide derived from human GIT1 around the phosphorylation site of Tyr545

亚型

IgG
anti-GIT1 (GIT1) (AA 460-640) antibody
KO Validated GIT1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-GIT1 (GIT1) (AA 470-642) antibody
GIT1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-GIT1 (GIT1) (AA 533-561), (C-Term), (Tyr554) antibody
GIT1 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB15351 unconjugated

anti-GIT1 (GIT1) (Internal Region) antibody
GIT1 适用: 人, 大鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-GIT1 (GIT1) (Internal Region) antibody
GIT1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-GIT1 (GIT1) (AA 375-770) antibody
GIT1 适用: 大鼠 WB, IP, IF, ICC 宿主: 小鼠 Monoclonal S39B-8 unconjugated

anti-GIT1 (GIT1) (AA 375-770) antibody (HRP)
GIT1 适用: 大鼠 WB, IP, IF, ICC 宿主: 小鼠 Monoclonal S39B-8 HRP

anti-GIT1 (GIT1) (AA 375-770) antibody (FITC)
GIT1 适用: 大鼠 WB, IP, IF, ICC 宿主: 小鼠 Monoclonal S39B-8 FITC

anti-GIT1 (GIT1) (AA 375-770) antibody (Biotin)
GIT1 适用: 大鼠 WB, IP, IF, ICC 宿主: 小鼠 Monoclonal S39B-8 Biotin

anti-GIT1 (GIT1) (AA 375-770) antibody (PE)
GIT1 适用: 大鼠 WB, IP, IF, ICC 宿主: 小鼠 Monoclonal S39B-8 PE

应用备注

IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

有效期

12 months
抗原

GIT1

别名

GIT1

背景

Synonyms: GIT1 phospho Tyr545, p-GIT1 Tyr545, ARF GAP GIT1, ARF GTPase activating protein GIT1, CAT 1, Cat1, Cool associated and tyrosine phosphorylated protein 1, G protein coupled receptor kinase interactor 1, GRK interacting protein 1.
Background: Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1,2). G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3,4). GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking (5,6). GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling (5).

基因ID

28964