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TNF alpha 抗体 (AA 1-234)
TNF alpha
适用: 人, 大鼠
WB, IHC (p), EIA
宿主: 小鼠
Monoclonal
M1-C4
unconjugated
TNF alpha抗体详情
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抗原
See all TNF alpha 抗体
TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
抗原表位
All epitopes for TNF alpha 抗体
AA 1-234
适用
All reactivities for TNF alpha 抗体
人, 大鼠
宿主
All hosts for TNF alpha 抗体
小鼠
克隆类型
All clonalities for TNF alpha 抗体
单克隆
标记
All conjugates for TNF alpha 抗体
This TNF alpha antibody is un-conjugated
应用范围
All applications for TNF alpha 抗体
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
特异性
This antibody reacts to TNF.
纯化方法
Affinity chromatography on Protein A
免疫原
TNF antibody was raised against tNF (AAH28148, 1 a.a. ~ 234 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
克隆位点
M1-C4
亚型
IgG1
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Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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浓度
0,5 mg/mL
缓冲液
PBS, pH 7.2
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
TNF alpha目标详情
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抗原
TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
别名
Tumor Necrosis Factor (TNF-Alpha) (TNF alpha 产品 )
别名
DIF antibody, TNF-alpha antibody, TNFA antibody, TNFSF2 antibody, RATTNF antibody, Tnfa antibody, tnf antibody, TNF-a antibody, TNFalpha antibody, Tnfsf1a antibody, TNFa antibody, cTNF antibody, Tnf-alpha antibody, tnfa-like antibody, TNF-ALPHA antibody, dif antibody, tnfa antibody, xtnf antibody, tnfsf2 antibody, tnf-alpha antibody, Cachectin antibody, tumor necrosis factor antibody, tumor necrosis factor b (TNF superfamily, member 2) antibody, tumor necrosis factor alpha antibody, tumor necrosis factor a (TNF superfamily, member 2) antibody, TNF antibody, Tnf antibody, tnf antibody, tnfb antibody, tnf-alpha antibody, LOC103694380 antibody, tnfa antibody
背景
Tumor Necrosis Factor (TNF) is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. TNF is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.Synonyms: Cachectin, TNF, TNF-a, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2
基因ID
7124
NCBI登录号
NP_000585
UniProt
P01375
途径
NF-kappaB Signaling , Apoptosis , Caspase Cascade in Apoptosis , TLR signaling , Cellular Response to Molecule of Bacterial Origin , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response , Positive Regulation of Endopeptidase Activity , Hepatitis C , Protein targeting to Nucleus , Inflammasome
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