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TNF alpha 抗体 (AA 1-234)

TNF alpha 适用: 人, 大鼠 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal M1-C4 unconjugated
产品编号 ABIN782382
发货至: 中国
  • 抗原 See all TNF alpha 抗体
    TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
    抗原表位
    • 47
    • 32
    • 15
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    • 13
    • 9
    • 6
    • 6
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    • 2
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-234
    适用
    • 318
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    • 122
    • 67
    • 50
    • 42
    • 27
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    • 16
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    • 10
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    • 6
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    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 262
    • 187
    • 30
    • 25
    • 6
    • 2
    • 2
    小鼠
    克隆类型
    • 278
    • 227
    单克隆
    标记
    • 242
    • 86
    • 45
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    • 17
    • 12
    • 6
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    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNF alpha antibody is un-conjugated
    应用范围
    • 346
    • 207
    • 128
    • 119
    • 74
    • 60
    • 54
    • 49
    • 48
    • 40
    • 39
    • 38
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to TNF.
    纯化方法
    Affinity chromatography on Protein A
    免疫原
    TNF antibody was raised against tNF (AAH28148, 1 a.a. ~ 234 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    克隆位点
    M1-C4
    亚型
    IgG1
    Top Product
    Discover our top product TNF alpha Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0,5 mg/mL
    缓冲液
    PBS, pH 7.2
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
    别名
    Tumor Necrosis Factor (TNF-Alpha) (TNF alpha 产品)
    别名
    DIF antibody, TNF-alpha antibody, TNFA antibody, TNFSF2 antibody, RATTNF antibody, Tnfa antibody, tnf antibody, TNF-a antibody, TNFalpha antibody, Tnfsf1a antibody, TNFa antibody, cTNF antibody, Tnf-alpha antibody, tnfa-like antibody, TNF-ALPHA antibody, dif antibody, tnfa antibody, xtnf antibody, tnfsf2 antibody, tnf-alpha antibody, Cachectin antibody, tumor necrosis factor antibody, tumor necrosis factor b (TNF superfamily, member 2) antibody, tumor necrosis factor alpha antibody, tumor necrosis factor a (TNF superfamily, member 2) antibody, TNF antibody, Tnf antibody, tnf antibody, tnfb antibody, tnf-alpha antibody, LOC103694380 antibody, tnfa antibody
    背景
    Tumor Necrosis Factor (TNF) is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. TNF is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.Synonyms: Cachectin, TNF, TNF-a, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2
    基因ID
    7124
    NCBI登录号
    NP_000585
    UniProt
    P01375
    途径
    NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
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