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SPTA1 抗体 (AA 1217-1267)

This 兔 多克隆 antibody specifically detects SPTA1 in WB. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN8124875
发货至: 中国
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Quick Overview for SPTA1 抗体 (AA 1217-1267) (ABIN8124875)

抗原

See all SPTA1 抗体
SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

适用

  • 88
  • 21
  • 13
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 47
  • 41
兔

克隆类型

  • 74
  • 14
多克隆

标记

  • 31
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
This SPTA1 antibody is un-conjugated

应用范围

  • 65
  • 60
  • 36
  • 13
  • 11
  • 11
  • 10
  • 4
  • 3
  • 2
  • 2
  • 2
Western Blotting (WB)
  • 抗原表位

    • 48
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1217-1267

    原理

    SPTA1 Antibody

    特异性

    This antibody detects endogenous levels of SPTA1 at Human/Mouse

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human SPTA1 AA range: 1217-1267

    亚型

    IgG
  • 应用备注

    WB 1:500-2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

    别名

    SPTA1

    背景

    Background: Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia. [provided by RefSeq, Jul 2008],

    Gene Name: SPTA1 SPTA

    Protein Name: SPTA1

    基因ID

    6708

    UniProt

    P02549

    途径

    Regulation of Actin Filament Polymerization
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