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SPTA1 抗体

SPTA1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7248185
发货至: 中国
  • 抗原 See all SPTA1 抗体
    SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))
    适用
    • 24
    • 11
    • 4
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 17
    • 8
    克隆类型
    • 13
    • 12
    多克隆
    标记
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPTA1 antibody is un-conjugated
    应用范围
    • 15
    • 8
    • 8
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Synthetic peptide of human SPTA1
    亚型
    IgG
    Top Product
    Discover our top product SPTA1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:60-1:450, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.7 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))
    别名
    SPTA1 (SPTA1 产品)
    别名
    Spna1 antibody, AF093576 antibody, AI451697 antibody, Spna-1 antibody, ha antibody, ihj antibody, nmf4 antibody, sph antibody, EL2 antibody, HPP antibody, HS3 antibody, SPH3 antibody, SPTA antibody, spectrin, alpha, erythrocytic 1 antibody, spectrin alpha, erythrocytic 1 antibody, Spta1 antibody, SPTA1 antibody
    背景
    Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.
    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 280 kDa

    UniProt
    P02549
    途径
    Regulation of Actin Filament Polymerization
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