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SQSTM1 抗体

The 兔 单克隆 anti-SQSTM1 antibody (Clone AB1652) (ABIN8124592) specifically detects SQSTM1 in WB, IHC, IF, ELISA 和 IP. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8124592
发货至: 中国
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Quick Overview for SQSTM1 抗体 (ABIN8124592)

抗原

See all SQSTM1 抗体
SQSTM1 (Sequestosome 1 (SQSTM1))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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单克隆

标记

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This SQSTM1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP)

克隆位点

AB1652
  • 原理

    SQSTM1/p62 Rabbit mAb

    特异性

    This antibody detects endogenous levels of SQSTM1/p62 protein.

    纯化方法

    The antibody was purified by protein A affinity chromatography.

    免疫原

    Recombinant protein (or fragment).

    亚型

    IgG
  • 应用备注

    WB, 1:500-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    SQSTM1 (Sequestosome 1 (SQSTM1))

    别名

    SQSTM1/p62

    背景

    Synonyms: Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)

    Background: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009],

    Gene Name: SQSTM1 ORCA OSIL

    Protein Name: SQSTM1/p62

    基因ID

    8878

    UniProt

    Q13501

    途径

    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
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