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Phospholipase C gamma 2 抗体 (pTyr759)

The 兔 多克隆 anti-Phospholipase C gamma 2 antibody (ABIN8123767) specifically detects Phospholipase C gamma 2 in WB, IHC, ELISA 和 IF. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN8123767
发货至: 中国
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Quick Overview for Phospholipase C gamma 2 抗体 (pTyr759) (ABIN8123767)

抗原

See all Phospholipase C gamma 2 (PLCG2) 抗体
Phospholipase C gamma 2 (PLCG2)

适用

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人, 小鼠

宿主

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兔

克隆类型

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多克隆

标记

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This Phospholipase C gamma 2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    pTyr759

    原理

    PLCγ2 (Phospho Tyr759) Antibody

    特异性

    This antibody detects endogenous levels of Human Mouse PLCγ2 (phospho-Tyr759)

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

    免疫原

    Synthesized phosho peptide around human PLCgamma2 (Tyr759)

    亚型

    IgG
  • 应用备注

    WB 1:500-2000, IF ICC 1:50-200,ELISA 1:2000-20000,IHC 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Phospholipase C gamma 2 (PLCG2)

    别名

    PLCgamma2

    背景

    Synonyms: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-IV) (PLC-IV) (Phospholipase C-gamma-2) (PLC-gamma-2)

    Background: The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014],

    Gene Name: PLCG2

    Protein Name: PLCγ2 (Tyr759)

    基因ID

    5336

    UniProt

    P16885

    途径

    RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
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