PIK3CA 抗体
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北京 101111
Quick Overview for PIK3CA 抗体 (ABIN8123759)
抗原
See all PIK3CA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PI3-Kinase p110α Rabbit mAb
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特异性
- This antibody detects endogenous levels of PI3-Kinase p110α protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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应用备注
- WB, 1:2000-1:10000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- PIK3CA (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))
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别名
- PI3-Kinase p110alpha
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背景
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Synonyms: 5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha,5-bisphosphate 3-kinase catalytic subunit alpha isoform,caPI3K,CLOVE,CWS5,MCAP,MCM,MCMTC,MGC142161,MGC142163,p110 alpha,p110alpha,Phosphatidylinositol 3 kinase catalytic alpha polypeptide,Phosphatidylinositol 3 kinase catalytic 110 KD alpha,Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha,Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha isoform,Phosphatidylinositol 4, 5 bisphosphate 3 kinase 110 kDa catalytic subunit alpha,Phosphatidylinositol-4,Phosphoinositide 3 kinase catalytic alpha polypeptide,PI 3 Kinase catalytic subunit alpha,PI3 kinase p110 subunit alpha,PI3-kinase subunit alpha,PI3K,PI3K-alpha,PI3KC A,PIK3C A,Pik3ca,PK3CA,PK3CA_HUMAN,PtdIns 3 kinase p110,PtdIns-3-kinase subunit alpha,PtdIns-3-kinase subunit p110-alpha,Serine/threonine protein kinase PIK3CA
Background: Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns (4, 5) P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22. [provided by RefSeq, Apr 2016]
Gene Name: PIK3CA
Protein Name: PI3-Kinase p110α
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基因ID
- 5290
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UniProt
- P42336
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途径
- PI3K-Akt Signaling, RTK signaling, TCR Signaling, AMPK Signaling, Interferon-gamma Pathway, TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, VEGF Signaling
抗原
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