PIK3CA 抗体 (AA 1000-1068)
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Quick Overview for PIK3CA 抗体 (AA 1000-1068) (ABIN8123751)
抗原
See all PIK3CA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1000-1068
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原理
- PIK3CA (H1047R) Mouse mAb (Ready to Use)
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特异性
- The antibody can specifically recognize humanPIK3CA H1047R protein.
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纯化方法
- The antibody was purified by protein G affinity chromatography.
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免疫原
- A synthetic peptide corresponding to the amino acid region 1000 - 1068 of the human PIK3CA protein.
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亚型
- IgG
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anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (AA 401-600) antibody
PIK3CA 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (AA 961-1068) antibodyPIK3CA 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) antibodyPIK3CA 适用: 人 WB, ELISA, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (AA 1019-1050), (C-Term) antibodyPIK3CA 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB01702 unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (pTyr317) antibodyPIK3CA 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (AA 504-533) antibodyPIK3CA 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (Internal Region) antibodyVerified PIK3CA 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (N-Term) antibodyPIK3CA 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (Catalytic Subunit) antibodyPIK3CA 适用: 人 WB, ELISA, IF 宿主: 兔 Monoclonal 10E5 unconjugated Recombinant Antibody
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (AA 1-206), (Catalytic Subunit) antibodyPIK3CA 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- It has been optimized for direct use, requiring no further dilution.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze
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储存条件
- 4 °C
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储存方法
- Store at 4°C. Avoid freeze.
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- PIK3CA (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))
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别名
- PIK3CA
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背景
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Synonyms: 5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha, 5-bisphosphate 3-kinase catalytic subunit alpha isoform, caPI3K, CLOVE, CWS5, MCAP, MCM, MCMTC, MGC142161, MGC142163, p110 alpha, p110alpha, Phosphatidylinositol 3 kinase catalytic alpha polypeptide, Phosphatidylinositol 3 kinase catalytic 110 KD alpha, Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha, Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha isoform, Phosphatidylinositol 4, 5 bisphosphate 3 kinase 110 kDa catalytic subunit alpha, Phosphatidylinositol-4, Phosphoinositide 3 kinase catalytic alpha polypeptide, PI 3 Kinase catalytic subunit alpha, PI3 kinase p110 subunit alpha, PI3-kinase subunit alpha, PI3K, PI3K-alpha, PI3KC A, PIK3C A, Pik3ca, PK3CA, PK3CA_HUMAN, PtdIns 3 kinase p110, PtdIns-3-kinase subunit alpha, PtdIns-3-kinase subunit p110-alpha, Serine/threonine protein kinase PIK3CA
Background: The PIK3CA gene is located at 3Q26. 3 and encodes a 124 kDa protein. The protein is composed of 85 kDa regulatory subunit and 110 kDa catalytic subunit. The most common mutations of PIK3CA occur in exon 9 and exon 20. H1047R, one of the most common mutations occurs in exon 20. PIK3CA plays an important role in the PI3K/AKT/mTOR signaling pathway, which can be activated by this mutation, closely related to the occurrence of tumors and disease progression. In non-small cell lung cancer, H1047R mutantion can phosphorylate Akt and activate downstream pathways to promote the survival and expansion of tumor cells.
Gene Name: PIK3CA
Protein Name: PIK3CA H1047R
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基因ID
- 5290
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UniProt
- P42336
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途径
- PI3K-Akt Signaling, RTK signaling, TCR Signaling, AMPK Signaling, Interferon-gamma Pathway, TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, VEGF Signaling
抗原
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