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MAP2K6 抗体 (pSer207)

The 兔 多克隆 anti-MAP2K6 antibody is suitable to detect MAP2K6 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN8123013
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MAP2K6 抗体 (pSer207) (ABIN8123013)

抗原

See all MAP2K6 抗体
MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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多克隆

标记

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This MAP2K6 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    pSer207

    原理

    MEK-6 (phospho Ser207) Antibody

    特异性

    Phospho-MEK-6 (S207) Polyclonal Antibody detects endogenous levels of MEK-6 protein only when phosphorylated at S207.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized phospho-peptide around the phosphorylation site of human MEK-6 (phospho Ser207)

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))

    别名

    MEK-6

    背景

    Synonyms: MAP2K6, MEK6, MKK6, PRKMK6, SKK3, Dual specificity mitogen-activated protein kinase kinase 6, MAP kinase kinase 6, MAPKK 6, MAPK/ERK kinase 6, MEK 6, Stress-activated protein kinase kinase 3, SAPK kinase 3, SAPKK-3, SAPKK3

    Background: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008],

    Gene Name: MAP2K6

    Protein Name: Dual specificity mitogen-activated protein kinase kinase 6

    基因ID

    5608

    UniProt

    P52564

    途径

    MAPK Pathway, TLR signaling, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
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