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MAP2K4 抗体 (pSer80)

The 兔 多克隆 anti-MAP2K4 antibody (ABIN8123008) specifically detects MAP2K4 in WB 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8123008
发货至: 中国
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Quick Overview for MAP2K4 抗体 (pSer80) (ABIN8123008)

抗原

See all MAP2K4 抗体
MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

适用

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人, 小鼠, 大鼠

宿主

  • 171
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兔

克隆类型

  • 171
  • 12
多克隆

标记

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This MAP2K4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    pSer80

    原理

    SEK1/MKK4 (Phospho Ser80) Antibody

    特异性

    This antibody detects endogenous levels of Human Mouse Rat SEK1/MKK4 (phospho-Ser80)

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

    免疫原

    Synthesized phosho peptide around human SEK1 (Ser80)

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:50-300

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

    别名

    SEK1/MKK4

    背景

    Synonyms: Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)

    Background: This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

    Gene Name: MAP2K4 JNKK1 MEK4 MKK4 PRKMK4 SEK1 SERK1 SKK1

    Protein Name: SEK1/MKK4 (Ser80)

    基因ID

    6416

    UniProt

    P45985

    途径

    MAPK Pathway, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling
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