电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

MAP2K4 抗体 (pSer257)

The 兔 多克隆 anti-MAP2K4 antibody is suitable to detect MAP2K4 in samples from 人, 小鼠 和 大鼠. It has been validated for IHC, ELISA 和 IF.
产品编号 ABIN8123007
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MAP2K4 抗体 (pSer257) (ABIN8123007)

抗原

See all MAP2K4 抗体
MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

适用

  • 178
  • 94
  • 74
  • 9
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 171
  • 11
兔

克隆类型

  • 171
  • 12
多克隆

标记

  • 91
  • 15
  • 11
  • 9
  • 6
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MAP2K4 antibody is un-conjugated

应用范围

  • 110
  • 72
  • 70
  • 26
  • 18
  • 16
  • 15
  • 11
  • 6
  • 5
  • 4
  • 3
  • 2
Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 40
    • 24
    • 18
    • 12
    • 12
    • 10
    • 9
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 223-272, pSer257

    原理

    MEK-4 (phospho Ser257) Antibody

    特异性

    Phospho-MEK-4 (S257) Polyclonal Antibody detects endogenous levels of MEK-4 protein only when phosphorylated at S257.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human SEK1/MKK4/JNKK1 around the phosphorylation site of Ser257. AA range:223-272

    亚型

    IgG
  • 应用备注

    IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

    别名

    MEK-4

    背景

    Synonyms: MAP2K4, JNKK1, MEK4, MKK4, PRKMK4, SEK1, SERK1, SKK1, Dual specificity mitogen-activated protein kinase kinase 4, MAP kinase kinase 4, MAPKK 4, JNK-activating kinase 1, MAPK/ERK kinase 4, MEK 4, SAPK/ERK kinase 1, SEK1, Stress-activated pro

    Background: This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

    Gene Name: MAP2K4

    Protein Name: Dual specificity mitogen-activated protein kinase kinase 4

    基因ID

    6416

    UniProt

    P45985

    途径

    MAPK Pathway, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling
You are here: