MAPK7 抗体
Our Local Distributor
北京 101111
Quick Overview for MAPK7 抗体 (ABIN8122995)
抗原
See all MAPK7 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- ERK 5 Antibody
-
特异性
- The antibody detects endogenous ERK 5 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Recombinant Protein of ERK 5
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:1000-2000 IHC 1:200-500. IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))
-
别名
- ERK 5
-
背景
-
Synonyms: MAPK7, BMK1, ERK5, PRKM7, Mitogen-activated protein kinase 7, MAP kinase 7, MAPK 7, Big MAP kinase 1, BMK-1, Extracellular signal-regulated kinase 5, ERK-5
Background: The protein encoded byThis gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008],
Gene Name: MAPK7,ERK5
Protein Name: Mitogen-activated protein kinase 7
-
基因ID
- 5598
-
UniProt
- Q13164
-
途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling
抗原
-