Recombinant MAPK7 抗体 (C-Term)
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Quick Overview for Recombinant MAPK7 抗体 (C-Term) (ABIN5557449)
抗原
See all MAPK7 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- ERK5 Recombinant Antibody
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交叉反应
- 人, 小鼠
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预测反应
- Rat
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant human ERK5 protein, around C-terminal 200aa.
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase 7 (MAPK7) (AA 1-310) antibody
MAPK7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 7 (MAPK7) (AA 185-419) antibodyMAPK7 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 7 (MAPK7) (AA 776-805) antibodyMAPK7 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 7 (MAPK7) (pSer731), (pThr733) antibodyMAPK7 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 7 (MAPK7) (pSer496) antibodyMAPK7 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 7 (MAPK7) (AA 411-556) antibodyMAPK7 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 8H1D5 unconjugated
anti-Mitogen-Activated Protein Kinase 7 (MAPK7) antibodyMAPK7 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 24GB290 unconjugated Recombinant Antibody
anti-Mitogen-Activated Protein Kinase 7 (MAPK7) (AA 776-805), (C-Term) antibodyMAPK7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0919 unconjugated
anti-Mitogen-Activated Protein Kinase 7 (MAPK7) (AA 401-500) antibodyMAPK7 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB(1:300-5000)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))
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别名
- ERK5
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背景
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Synonyms: BMK1, ERK4, ERK5, PRKM7, Mitogen-activated protein kinase 7, MAP kinase 7, MAPK 7, Big MAP kinase 1, BMK-1, Extracellular signal-regulated kinase 5, ERK-5, MAPK7
Background: Plays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway. May have a role in muscle cell differentiation. May be important for endothelial function and maintenance of blood vessel integrity. MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression. Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 interaction.
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基因ID
- 5598
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UniProt
- Q13164
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途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling
抗原
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