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CD51 抗体 (Cleaved-Asp891, Light Chain)

The 兔 多克隆 anti-CD51 antibody (ABIN8122252) specifically detects CD51 in WB, IHC 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN8122252
发货至: 中国
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Quick Overview for CD51 抗体 (Cleaved-Asp891, Light Chain) (ABIN8122252)

抗原

See all CD51 (ITGAV) 抗体
CD51 (ITGAV) (Integrin alpha V (ITGAV))

适用

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人, 小鼠

宿主

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兔

克隆类型

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  • 75
多克隆

标记

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This CD51 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 26
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    Cleaved-Asp891, Light Chain

    原理

    ITGAV (light chain, Cleaved-Asp891) Antibody

    特异性

    This antibody detects endogenous levels of Human,Mouse ITGAV (light chain, Cleaved-Asp891, protein was cleaved amino acid sequence between 890-891 )

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

    免疫原

    Synthesized peptide derived from human ITGAV (light chain, Cleaved-Asp891)

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    CD51 (ITGAV) (Integrin alpha V (ITGAV))

    别名

    ITGAV

    背景

    Synonyms: Integrin alpha-V (Vitronectin receptor subunit alpha, CD antigen CD51) [Cleaved into: Integrin alpha-V heavy chain, Integrin alpha-V light chain]

    Background: integrin subunit alpha V(ITGAV) Homo sapiens The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015],

    Gene Name: ITGAV MSK8 VNRA

    Protein Name: ITGAV (light chain, Cleaved-Asp891)

    基因ID

    3685

    UniProt

    P06756

    途径

    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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