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ICOSLG 抗体 (AA 201-250)

The 兔 多克隆 anti-ICOSLG antibody (ABIN8122180) specifically detects ICOSLG in IHC, ELISA 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8122180
发货至: 中国
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Quick Overview for ICOSLG 抗体 (AA 201-250) (ABIN8122180)

抗原

See all ICOSLG 抗体
ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

适用

  • 112
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  • 2
  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 58
  • 54
  • 5
  • 5
  • 1
兔

克隆类型

  • 80
  • 42
  • 1
多克隆

标记

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This ICOSLG antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 30
    • 7
    • 5
    • 5
    • 5
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    • 4
    • 3
    • 3
    • 2
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    • 1
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    AA 201-250

    原理

    CD275 Antibody

    特异性

    The antibody detects endogenous CD275

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthetic peptide from human protein at AA range: 201-250

    亚型

    IgG
  • 应用备注

    IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

    别名

    CD275

    背景

    Synonyms: ICOS ligand (B7 homolog 2, B7-H2, B7-like protein Gl50, B7-related protein 1, B7RP-1, CD antigen CD275)

    Background: alternative products:Additional isoforms seem to exist,function:Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion, induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.,induction:Constitutive expression is further enhanced by treatment with TNF-alpha in peripheral blood B-cells and monocytes, while it is decreased in dendritic cells.,sequence caution:The sequence differs from that shown in position 300 onward for unknown reason.,sequence caution:Translation N-terminally shortened.,similarity:Belongs to the immunoglobulin superfamily. BTN/MOG family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,tissue specificity:Isoform 1 is widely expressed (brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, bone marrow, colon, ovary, prostate, testis, lymph nodes, leukocytes, spleen, thymus and tonsil), while isoform 2 is detected only in lymph nodes, leukocytes and spleen. Expressed on activated monocytes and dendritic cells.,

    Gene Name: ICOSLG B7H2 B7RP1 ICOSL KIAA0653

    Protein Name: ICOS ligand (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD antigen CD275)

    基因ID

    23308

    UniProt

    O75144

    途径

    Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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