GTPase NRas 抗体
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北京 101111
Quick Overview for GTPase NRas 抗体 (ABIN8121836)
抗原
See all GTPase NRas (NRAS) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- NRAS Rabbit mAb
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特异性
- This antibody detects endogenous levels of NRAS protein.
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纯化方法
- The antibody was purified by protein A affinity chromatography.
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免疫原
- Recombinant protein (or fragment).
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亚型
- IgG
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anti-GTPase NRas (NRAS) (Internal Region) antibody
Verified NRAS 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-GTPase NRas (NRAS) (AA 72-101), (N-Term) antibodyNRAS 适用: 人, 大鼠, 小鼠 WB, FACS, IF 宿主: 兔 Polyclonal RB14459 unconjugated
anti-GTPase NRas (NRAS) (AA 72-101) antibodyNRAS 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-GTPase NRas (NRAS) (AA 101-189) antibodyNRAS 适用: 人 WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-GTPase NRas (NRAS) antibodyNRAS 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-GTPase NRas (NRAS) (AA 91-140) antibodyNRAS 适用: 人, 大鼠, 小鼠, Cow, 马, 豚鼠, 兔, 斑马鱼, Bat, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GTPase NRas (NRAS) (AA 147-179) antibodyNRAS 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-GTPase NRas (NRAS) antibodyNRAS 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB56819 unconjugated
anti-GTPase NRas (NRAS) (AA 70-101), (N-Term) antibodyNRAS 适用: 人, 大鼠 WB 宿主: 小鼠 Monoclonal 822CT17-5-1 unconjugated
anti-GTPase NRas (NRAS) (AA 1-186) antibodyNRAS 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at-20°C. Avoid freeze / thaw cycles.
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- GTPase NRas (NRAS)
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别名
- NRAS
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背景
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Synonyms: GTPase NRas (Transforming protein N-Ras)
Background: This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]
Gene Name: NRAS HRAS1
Protein Name: NRAS
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基因ID
- 4893
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UniProt
- P01111
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途径
- p53 Pathway, MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
抗原
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