GBL 抗体 (AA 100-180)
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北京 101111
Quick Overview for GBL 抗体 (AA 100-180) (ABIN8121551)
抗原
See all GBL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-180
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原理
- LST8 Antibody
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特异性
- LST8 Polyclonal Antibody detects endogenous levels of protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human protein . at AA range: 100-180
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亚型
- IgG
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anti-G protein beta subunit-like (GBL) (AA 1-326) antibody
GBL 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-G protein beta subunit-like (GBL) (AA 1-326) antibodyGBL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-G protein beta subunit-like (GBL) (C-Term) antibodyGBL 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G protein beta subunit-like (GBL) (AA 1-326) antibodyGBL 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-G protein beta subunit-like (GBL) (AA 159-220) antibodyGBL 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-G protein beta subunit-like (GBL) (AA 284-313), (C-Term) antibodyGBL 适用: 人 WB 宿主: 兔 Polyclonal RB40209 unconjugated
anti-G protein beta subunit-like (GBL) (C-Term) antibodyGBL 适用: 人, 小鼠, 大鼠, Cow, 犬, 山羊, 豚鼠, 兔, 马, 猴, Pig, Hamster, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-G protein beta subunit-like (GBL) antibodyGBL 适用: 小鼠 WB 宿主: 小鼠 Monoclonal 211CT7-1-1 unconjugated
anti-G protein beta subunit-like (GBL) (AA 1-326) antibodyGBL 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB 1:500-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GBL (G protein beta subunit-like (GBL))
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别名
- LST8
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背景
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Background: function:Unessential component of the TORC1 complex and essential component of the TORC2 complex. TORC1 controls cell growth in response to environmental signals, and is inactivated by nutrient limitation and environmental stress. Within TORC1, LST8 interacts directly with FRAP1 and enhances its kinase activity. In nutrient-poor conditions, stabilizes the FRAP1-RAPTOR interaction and favors RAPTOR-mediated inhibition of FRAP1 activity. TORC2 controls polarity of the actin cytoskeleton via the RAC1 pathway. TORC2 mediates phosphorylation of Akt/PKB on 'Ser-473' and phosphorylation of PKCalpha on 'Ser-657'.,similarity:Belongs to the WD repeat LST8 family.,similarity:Contains 7 WD repeats.,subunit:Interacts with FRAP1, RAPTOR and RHEB. Part of the target of rapamycin complex 1 (TORC1) which contains LST8, FRAP1, RAPTOR and AKT1S1. TORC1 binds to and is inhibited by FKBP12-rapamycin. Part of the target of rapamycin complex 2 (TORC2) which contains FRAP1, LST8, PROTOR1, RICTOR and MAPKAP1. Contrary to TORC1, TORC2 does not bind to and is not sensitive to FKBP12-rapamycin.,tissue specificity:Broadly expressed, with highest levels in skeletal muscle, heart and kidney.,
Gene Name: MLST8 GBL LST8
Protein Name: Target of rapamycin complex subunit LST8 (TORC subunit LST8) (G protein beta subunit-like) (Gable) (Protein GbetaL) (Mammalian lethal with SEC13 protein 8) (mLST8)
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基因ID
- 64223
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UniProt
- Q9BVC4
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途径
- PI3K-Akt Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effect
抗原
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