CFHR5 抗体 (AA 353-403)
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北京 101111
Quick Overview for CFHR5 抗体 (AA 353-403) (ABIN8120724)
抗原
See all CFHR5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 353-403
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原理
- FHR5 Antibody
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特异性
- This antibody detects endogenous levels of FHR5 at Human
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human FHR5 AA range: 353-403
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亚型
- IgG
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应用备注
- WB 1:500-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CFHR5 (Complement Factor H-Related 5 (CFHR5))
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别名
- FHR5
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背景
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Synonyms: Complement factor H-related protein 5 (FHR-5)
Background: This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation.The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq, Jan 2010],
Gene Name: CFHR5 CFHL5 FHR5
Protein Name: FHR5
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基因ID
- 81494
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UniProt
- Q9BXR6
抗原
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