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CFHR5 抗体 (AA 353-403)

The 兔 多克隆 anti-CFHR5 antibody is suitable to detect CFHR5 in samples from 人, 小鼠 和 大鼠. It has been validated for WB.
产品编号 ABIN8120724
发货至: 中国
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Quick Overview for CFHR5 抗体 (AA 353-403) (ABIN8120724)

抗原

See all CFHR5 抗体
CFHR5 (Complement Factor H-Related 5 (CFHR5))

适用

人, 小鼠, 大鼠

宿主

  • 23
  • 13
兔

克隆类型

  • 24
  • 12
多克隆

标记

  • 21
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CFHR5 antibody is un-conjugated

应用范围

  • 25
  • 14
  • 14
  • 13
  • 4
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 353-403

    原理

    FHR5 Antibody

    特异性

    This antibody detects endogenous levels of FHR5 at Human

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human FHR5 AA range: 353-403

    亚型

    IgG
  • 应用备注

    WB 1:500-2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    CFHR5 (Complement Factor H-Related 5 (CFHR5))

    别名

    FHR5

    背景

    Synonyms: Complement factor H-related protein 5 (FHR-5)

    Background: This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation.The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq, Jan 2010],

    Gene Name: CFHR5 CFHL5 FHR5

    Protein Name: FHR5

    基因ID

    81494

    UniProt

    Q9BXR6
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