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CFHR5 抗体 (AA 450-569)

CFHR5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6138459
发货至: 中国
  • 抗原 See all CFHR5 抗体
    CFHR5 (Complement Factor H-Related 5 (CFHR5))
    抗原表位
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    AA 450-569
    适用
    • 36
    • 10
    宿主
    • 24
    • 12
    克隆类型
    • 25
    • 11
    多克隆
    标记
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CFHR5 antibody is un-conjugated
    应用范围
    • 26
    • 19
    • 16
    • 15
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    GPPPSINNGD TTSFPLSVYP PGSTVTYRCQ SFYKLQGSVT VTCRNKQWSE PPRCLDPCVV SEENMNKNNI QLKWRNDGKL YAKTGDAVEF QCKFPHKAMI SSPPFRAICQ EGKFEYPICE
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 450-569 of human CFHR5 (NP_110414.1).
    亚型
    IgG
    Top Product
    Discover our top product CFHR5 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CFHR5 (Complement Factor H-Related 5 (CFHR5))
    别名
    CFHR5 (CFHR5 产品)
    别名
    CFHL5 antibody, CFHR5D antibody, FHR-5 antibody, FHR5 antibody, complement factor H related 5 antibody, CFHR5 antibody
    背景
    This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS).,CFHR5,CFHL5,CFHR5D,FHR-5,FHR5,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,CFHR5
    分子量
    64 kDa
    基因ID
    81494
    UniProt
    Q9BXR6
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