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CTCF 抗体

The 兔 单克隆 anti-CTCF antibody is suitable to detect CTCF in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, IF, ELISA 和 IP.
产品编号 ABIN8120295
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CTCF 抗体 (ABIN8120295)

抗原

See all CTCF 抗体
CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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单克隆

标记

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This CTCF antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP)

克隆位点

AB2111
  • 原理

    CTCF Rabbit mAb

    特异性

    This antibody detects endogenous levels of CTCF protein.

    纯化方法

    The antibody was purified by protein A affinity chromatography.

    免疫原

    Recombinant protein (or fragment).

    亚型

    IgG
  • 应用备注

    WB, 1:2000-1:10000 | IHC, 1:2000-1:10000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at-20°C. Avoid freeze / thaw cycles.
  • 抗原

    CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

    别名

    CTCF

    背景

    Synonyms: CTCF, Transcriptional repressor CTCF, 11-zinc finger protein, CCCTC-binding factor, CTCFL paralog

    Background: This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms&apos, tumors. Alternatively spliced transcript variants encoding different isoforms have been

    Gene Name: CTCF

    Protein Name: CTCF

    基因ID

    10664

    UniProt

    P49711
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