ATM 抗体 (pSer1987)
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北京 101111
Quick Overview for ATM 抗体 (pSer1987) (ABIN8119834)
抗原
See all ATM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer1987
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原理
- ATM (Phospho Ser1987) Antibody
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特异性
- This antibody detects endogenous levels of Human,Mouse,Rat ATM (Phospho Ser1987)
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthesized peptide derived from human ATM (Phospho Ser1987)
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亚型
- IgG
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anti-Ataxia Telangiectasia Mutated (ATM) (AA 1974-1988), (pSer1981) antibody
ATM 适用: 人 WB, IHC, ELISA, IF, IP, FACS, FM 宿主: 小鼠 Monoclonal 10H11-E12 unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (AA 1974-1988), (pSer1981) antibodyATM 适用: 人 WB, IHC, ELISA, IF, IP, FACS, FM 宿主: 小鼠 Monoclonal 10H11-E12 unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (AA 2681-2750) antibodyATM 适用: 小鼠 WB, IHC (p), FACS, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) antibodyATM 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Monoclonal 4E11 unconjugated Recombinant Antibody
anti-Ataxia Telangiectasia Mutated (ATM) (AA 2484-2748) antibodyATM 适用: 人 IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (C-Term) antibodyATM 适用: 人, 小鼠 WB, IHC, ELISA, IF, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) (AA 2550-2600) antibodyATM 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Monoclonal BLR359N unconjugated Recombinant Antibody
anti-Ataxia Telangiectasia Mutated (ATM) (pSer1981) antibodyATM 适用: 人 IF, DB 宿主: 兔 Polyclonal RB8121 unconjugated
anti-Ataxia Telangiectasia Mutated (ATM) antibodyATM 适用: 人 IHC, ELISA, FACS 宿主: 兔 Monoclonal 3G11 unconjugated Recombinant Antibody
anti-Ataxia Telangiectasia Mutated (ATM) antibodyKD Validated ATM 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2830 unconjugated Recombinant Antibody
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应用备注
- WB 1:1000-2000 ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ATM (Ataxia Telangiectasia Mutated (ATM))
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别名
- ATM
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背景
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Synonyms: Serine-protein kinase ATM (EC 2.7.11.1, Ataxia telangiectasia mutated, A-T mutated)
Background: The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates, thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010],
Gene Name: ATM
Protein Name: ATM (Phospho Ser1987)
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基因ID
- 472
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UniProt
- Q62388
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途径
- p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
抗原
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