ADAMTS8 抗体 (AA 541-640) (Cy7)
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- 抗原 See all ADAMTS8 抗体
- ADAMTS8 (ADAM Metallopeptidase with thrombospondin Type 1 Motif, 8 (ADAMTS8))
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抗原表位
- AA 541-640
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ADAMTS8 antibody is conjugated to Cy7
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Pig,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ADAMTS8
- 亚型
- IgG
- Top Product
- Discover our top product ADAMTS8 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- ADAMTS8 (ADAM Metallopeptidase with thrombospondin Type 1 Motif, 8 (ADAMTS8))
- 别名
- ADAMTS8 (ADAMTS8 产品)
- 别名
- ADAMTS8 antibody, METH-2 antibody, METH2 antibody, ADAM-TS8 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 8 antibody, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8 antibody, ADAM metallopeptidase with thrombospondin type 1 motif, 8 antibody, ADAMTS8 antibody, adamts8 antibody, Adamts8 antibody
- 背景
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Synonyms: A disintegrin and metalloproteinase with thrombospondin mots 8, ADAMTS 8, METH 2, METH 8, METH8, A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 mot 8, A disintegrin like and metalloprotease with thrombospondin type 1 mot 8, ADAM metallopeptidase with thrombospondin type 1 mot 8, ADAM TS 8, ADAM TS8, METH2, ATS8_HUMAN.
Background: ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration.A member of the metalloproteinase family containing disintegrin like domains (ADAMs), the function of ADAMTS8 is still poorly understood. ADAMTS8 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, and has been shown to be proteolytically active on a range of substrates. ADAMTS8 is inhibited by the endogenous MMP inhibitors, TIMP1, 2, 3 and 4, but most efficiently by TIMP3. In addition to the metalloprotease domain, ADAMTS8 has a propeptide domain, a Prohormone Convertase (PC, furin) cleavage site, a cysteine rich domain and thrombospondin 1 like domains.
- 基因ID
- 11095
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