RHOA 抗体 (pSer188)
(2 references)Quick Overview for RHOA 抗体 (pSer188) (ABIN758242)
抗原
See all RHOA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer188
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Sheep,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human RhoA around the phosphorylation site of Ser188
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亚型
- IgG
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anti-Ras Homolog Gene Family, Member A (RHOA) (AA 1-193) antibody
RHOA 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1B12 unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (AA 1-193) antibodyRHOA 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 1C1 unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (AA 100-150) antibodyRHOA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (C-Term) antibodyRHOA 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (AA 1-194) antibodyRHOA 适用: 人 WB, ELISA, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 1B12 unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (C-Term) antibodyRHOA 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (AA 1-193) antibodyKO Validated RHOA 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (AA 1-191) antibodyRHOA 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (AA 1-193) antibodyRHOA 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (AA 180-184) antibodyRHOA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Fasudil attenuates soluble fms-like tyrosine kinase-1 (sFlt-1)-induced hypertension in pregnant mice through RhoA/ROCK pathway." in: Oncotarget, Vol. 8, Issue 61, pp. 104104-104112, (2017) (PubMed).
: "HSF1 Relieves Amyloid-?-Induced Cardiomyocytes Apoptosis." in: Cell biochemistry and biophysics, (2015) (PubMed).
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: "Fasudil attenuates soluble fms-like tyrosine kinase-1 (sFlt-1)-induced hypertension in pregnant mice through RhoA/ROCK pathway." in: Oncotarget, Vol. 8, Issue 61, pp. 104104-104112, (2017) (PubMed).
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- RHOA (Ras Homolog Gene Family, Member A (RHOA))
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别名
- RhoA
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背景
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Synonyms: RHOAphospho S188, RhoA protein, Aplysia ras related homolog 12, ARH 12, ARH12, ARHA, H 12, Oncogene RHO H12, Ras homolog gene family member A, RHO 12, Rho A, RHO H12, RHO12, RHOH 12, RHOH12, Small GTP binding protein Rho A, Small GTP binding protein RhoA, Transforming protein Rho A, Transforming protein RhoA.
Background: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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基因ID
- 387
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途径
- Microtubule Dynamics, WNT signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, SARS-CoV-2 Protein Interactome
抗原
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