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KAP1 抗体 (AA 699-835) (Fluoro488)

The 小鼠 单克隆 anti-KAP1 antibody is suitable to detect KAP1 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN8049771
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for KAP1 抗体 (AA 699-835) (Fluoro488) (ABIN8049771)

抗原

See all KAP1 (TRIM28) 抗体
KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

适用

  • 170
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  • 10
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  • 1
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人, 小鼠, 大鼠

宿主

  • 147
  • 40
  • 4
  • 1
小鼠

克隆类型

  • 121
  • 71
单克隆

标记

  • 79
  • 13
  • 11
  • 7
  • 6
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  • 2
  • 2
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  • 2
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  • 1
This KAP1 antibody is conjugated to Fluoro488

应用范围

  • 118
  • 73
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  • 44
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  • 32
  • 27
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  • 23
  • 12
  • 4
  • 4
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  • 2
  • 2
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  • 1
  • 1
  • 1
Flow Cytometry (FACS)

克隆位点

3H2
  • 抗原表位

    • 37
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    • 15
    • 9
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    • 6
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    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 699-835

    原理

    Anti-KAP1/TRIM28 Antibody (monoclonal, 3H2) Fluoro488 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    Human KAP1 shares 94.9% amino acid (aa) sequence identity with both mouse,rat KAP1.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human KAP1 recombinant protein (Position: A699-P835). Human KAP1 shares 94.9% amino acid (aa) sequence identity with both mouse and rat KAP1.

    亚型

    IgG2b
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

    别名

    TRIM28

    背景

    Background: Tripartite motif-containing 28 (TRIM28), also known as transcriptional intermediary factor 1β (TIF1β) and KAP1 (KRAB-associated protein-1), is a protein that in humans is encoded by the TRIM28 gene. The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. KAP1 is a ubiquitously expressed protein involved in many critical functions including: transcriptional regulation, cellular differentiation and proliferation, DNA damage repair, viral suppression, and apoptosis. Its functionality is dependent upon post-translational modifications. Phosphorylation of KAP1 acts as a deactivator of the protein in many of its mechanisms while sumoylation acts as an activator.

    Gene Full Name: tripartite motif containing 28

    基因ID

    10155

    UniProt

    Q13263

    途径

    Hedgehog Signaling, Positive Regulation of Response to DNA Damage Stimulus
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