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TDG 抗体 (AA 15-370) (Fluoro550)

This 兔 多克隆 antibody specifically detects TDG in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8046536
发货至: 中国
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Quick Overview for TDG 抗体 (AA 15-370) (Fluoro550) (ABIN8046536)

抗原

See all TDG 抗体
TDG (Thymine-DNA Glycosylase (TDG))

适用

  • 61
  • 29
  • 21
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 49
  • 12

克隆类型

  • 52
  • 10
多克隆

标记

  • 46
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TDG antibody is conjugated to Fluoro550

应用范围

  • 44
  • 18
  • 14
  • 13
  • 13
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 12
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 15-370

    原理

    Anti-TDG Antibody Fluoro550 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human TDG recombinant protein (Position: Q15-R370).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    TDG (Thymine-DNA Glycosylase (TDG))

    别名

    TDG

    背景

    Background: G/T mismatch-specific thymine DNA glycosylase is an enzyme that in humans is encoded by the TDG gene. The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12.

    Gene Full Name: thymine DNA glycosylase

    基因ID

    6996

    UniProt

    Q13569

    途径

    DNA Damage Repair, Chromatin Binding
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