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SMAD3 抗体 (Middle Region) (APC)

The 兔 多克隆 anti-SMAD3 antibody is suitable to detect SMAD3 in samples from 人, 小鼠 和 大鼠. It has been validated for WB.
产品编号 ABIN8038176
发货至: 中国
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Room 801-803
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Quick Overview for SMAD3 抗体 (Middle Region) (APC) (ABIN8038176)

抗原

See all SMAD3 抗体
SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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多克隆

标记

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This SMAD3 antibody is conjugated to APC

应用范围

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Western Blotting (WB)
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    Middle Region

    原理

    Anti-Smad3 Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    identical to the related mouse,rat sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human Smad3, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat

    说明

    Applications are recommended based on the unconjugated antibody.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

    别名

    SMAD3

    背景

    Background: Mothers against decapentaplegic homolog 3 also known as SMAD family member 3 or SMAD3 is a protein that in humans is encoded by the SMAD3 gene. SMAD3 is a member of the SMAD family of proteins. It is located in 15q22.33. And it mediates the signals from the transforming growth factor beta (TGF-β) super family ligands that regulate cell proliferation, differentiation and death. Based on its essential role in TGF beta signaling pathway, SMAD3 has been related with tumor growth in cancer development.

    Gene Full Name: SMAD family member 3

    Sequence Similarities: Belongs to the dwarfin/SMAD family.

    基因ID

    4088

    UniProt

    P84022

    途径

    Cell Division Cycle, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy
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