SGK1 抗体 (N-Term)
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Quick Overview for SGK1 抗体 (N-Term) (ABIN8036600)
抗原
See all SGK1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- N-Term
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原理
- Anti-SGK1 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- different from the related mouse sequence by three amino acids,and from the related rat sequence by one amino acid.
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产品特性
- Anti-SGK1 Antibody. Tested in WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human SGK1, different from the related mouse sequence by three amino acids, and from the related rat sequence by one amino acid.
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亚型
- IgG
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))
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别名
- SGK1
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背景
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Background: Serine/threonine-protein kinase Sgk1, also called SGK1, encodes a serine/threonine protein kinase that plays an important role in cellular stress response. By fluorescence in situ hybridization, this gene is mapped to 6q23.2. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Gene Full Name: serum/glucocorticoid regulated kinase 1
Sequence Similarities: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
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分子量
- 49 kDa
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基因ID
- 6446
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UniProt
- O00141
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途径
- MAPK Pathway, Notch Signaling, Steroid Hormone Mediated Signaling Pathway
抗原
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