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PIM1 抗体 (C-Term) (FITC)

The 兔 多克隆 anti-PIM1 antibody is suitable to detect PIM1 in samples from 人. It has been validated for FACS.
产品编号 ABIN8022573
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for PIM1 抗体 (C-Term) (FITC) (ABIN8022573)

抗原

See all PIM1 抗体
PIM1 (Pim-1 Oncogene (PIM1))

适用

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宿主

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克隆类型

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多克隆

标记

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This PIM1 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    C-Term

    原理

    Anti-PIM1 Antibody FITC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse sequence by seven amino acids,from the related rat sequence by two amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human PIM1, different from the related mouse sequence by seven amino acids and from the related rat sequence by two amino acids.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    PIM1 (Pim-1 Oncogene (PIM1))

    别名

    PIM1

    背景

    Background: Proto-oncogene serine/threonine-protein kinase Pim-1 is an enzyme that in humans is encoded by the PIM1 gene. It is mapped to 6p21.2. Primarily expressed in spleen, thymus, bone marrow, prostate, oral epithelial, hippocampus and fetal liver cells, Pim-1 has also been found to be highly expressed in cell cultures isolated from human tumors. Pim-1 is mainly involved in cell cycle progression, apoptosis and transcriptional activation, as well as more general signal transduction pathways. It has been found a physiologic role of the PIM1 oncogene during hematopoietic development and a deregulation of the gene in various leukemias. PIM1 also has a role in cardioprotection downstream of AKT activation.

    Gene Full Name: Pim-1 proto-oncogene, serine/threonine kinase

    Sequence Similarities: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.

    基因ID

    5292

    UniProt

    P11309

    途径

    Glycosaminoglycan Metabolic Process
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