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PIM1 抗体 (C-Term)

PIM1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB34666 unconjugated
产品编号 ABIN657998
发货至: 中国
  • 抗原 See all PIM1 抗体
    PIM1 (Pim-1 Oncogene (PIM1))
    抗原表位
    • 18
    • 16
    • 14
    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 343-372, C-Term
    适用
    • 100
    • 46
    • 46
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 101
    • 9
    克隆类型
    • 92
    • 18
    多克隆
    标记
    • 43
    • 16
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This PIM1 antibody is un-conjugated
    应用范围
    • 92
    • 51
    • 28
    • 27
    • 26
    • 16
    • 14
    • 8
    • 6
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Mouse Pim1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-372 amino acids from the C-terminal region of mouse Pim1.
    克隆位点
    RB34666
    亚型
    Ig Fraction
    Top Product
    Discover our top product PIM1 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Mouse Pim1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    有效期
    6 months
  • 抗原
    PIM1 (Pim-1 Oncogene (PIM1))
    别名
    Pim1 (PIM1 产品)
    别名
    PIM antibody, Pim-1 antibody, PIM1 antibody, pim antibody, pim-1 antibody, pim3 antibody, Pim-1 proto-oncogene, serine/threonine kinase antibody, proviral integration site 1 antibody, Pim-1 proto-oncogene, serine/threonine kinase L homeolog antibody, PIM1 antibody, Pim1 antibody, pim1 antibody, pim1.L antibody
    背景
    Pim1 may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3 (By similarity). Promotes the G1/S transition of the cell cycle via up-regulation of CDK2 activity and phosphorylation of CDKN1B, resulting in enhanced nuclear export and proteasome-dependent degradation of CDKN1B (By similarity). Also represses CDKN1B transcription by phosphorylating and inactivating the transcription factor FOXO3 (By similarity). Plays a role in signal transduction in blood cells (By similarity). Contributes to both cell proliferation and survival thus providing a selective advantage in tumorigenesis (By similarity).
    分子量
    35451
    基因ID
    18712
    UniProt
    P06803
    途径
    Glycosaminoglycan Metabolic Process
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