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PIM1 抗体 (C-Term)

PIM1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1285-RB1286 unconjugated
产品编号 ABIN392440
发货至: 中国
  • 抗原 See all PIM1 抗体
    PIM1 (Pim-1 Oncogene (PIM1))
    抗原表位
    • 19
    • 16
    • 14
    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 374-404, C-Term
    适用
    • 103
    • 48
    • 47
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 104
    • 9
    克隆类型
    • 93
    • 20
    多克隆
    标记
    • 46
    • 16
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This PIM1 antibody is un-conjugated
    应用范围
    • 95
    • 52
    • 28
    • 27
    • 26
    • 17
    • 14
    • 9
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    B
    纯化方法
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    This PIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-404 amino acids from the C-terminal region of human PIM1.
    克隆位点
    RB1285-RB1286
    亚型
    Ig Fraction
    Top Product
    Discover our top product PIM1 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Albertson, Schmidt, Bearss, Tripp, Bearss, Liu: "Patterns and Significance of PIM Kinases in Urothelial Carcinoma." in: Applied immunohistochemistry & molecular morphology : AIMM, Vol. 23, Issue 10, pp. 717-23, (2016) (PubMed).

    Plum, Warnecke-Eberz, Dhaouadi, Alakus, Drebber, Metzger, Prenzel, Hölscher, Bollschweiler: "Molecular markers predicting lymph node metastasis in early esophageal cancer." in: Histology and histopathology, pp. 11618, (2015) (PubMed).

    Warnecke-Eberz, Bollschweiler, Drebber, Metzger, Baldus, Hölscher, Mönig: "Prognostic impact of protein overexpression of the proto-oncogene PIM-1 in gastric cancer." in: Anticancer research, Vol. 29, Issue 11, pp. 4451-5, (2009) (PubMed).

    Chen, Kobayashi, Darmanin, Qiao, Gully, Zhao, Kondo, Wang, Wang, Yeung, Lee: "Hypoxia-mediated up-regulation of Pim-1 contributes to solid tumor formation." in: The American journal of pathology, Vol. 175, Issue 1, pp. 400-11, (2009) (PubMed).

    Reiser-Erkan, Erkan, Pan, Bekasi, Giese, Streit, Michalski, Friess, Kleeff: "Hypoxia-inducible proto-oncogene Pim-1 is a prognostic marker in pancreatic ductal adenocarcinoma." in: Cancer biology & therapy, Vol. 7, Issue 9, pp. 1352-9, (2008) (PubMed).

    Wallentine, Kim, Seiler, Vaughn, Crockett, Tripp, Elenitoba-Johnson, Lim: "Comprehensive identification of proteins in Hodgkin lymphoma-derived Reed-Sternberg cells by LC-MS/MS." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 87, Issue 11, pp. 1113-24, (2007) (PubMed).

  • 抗原
    PIM1 (Pim-1 Oncogene (PIM1))
    别名
    PIM1 (PIM1 产品)
    别名
    PIM antibody, Pim-1 antibody, PIM1 antibody, pim antibody, pim-1 antibody, pim3 antibody, Pim-1 proto-oncogene, serine/threonine kinase antibody, proviral integration site 1 antibody, Pim-1 proto-oncogene, serine/threonine kinase L homeolog antibody, PIM1 antibody, Pim1 antibody, pim1 antibody, pim1.L antibody
    背景
    PIM1, which belongs to the Serine/Threonine protein kinase family, is thought to play a role in signal transduction in blood cells. The protooncogene PIM1 encodes a protein kinase upregulated in prostate cancer. It may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. PIM1 is expressed primarily in cells of the hematopoietic and germ line lineages.
    分子量
    35686
    基因ID
    5292
    NCBI登录号
    NP_001230115, NP_002639
    UniProt
    P11309
    途径
    Glycosaminoglycan Metabolic Process
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