电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

PRKACA 抗体 (AA 101-200) (Cy3)

PRKACA 适用: 小鼠 WB, IF (p), IF (cc) 宿主: 兔 Polyclonal Cy3
产品编号 ABIN751891
发货至: 中国
  • 抗原 See all PRKACA 抗体
    PRKACA (Protein Kinase A, alpha (PRKACA))
    抗原表位
    • 14
    • 10
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    适用
    • 57
    • 37
    • 14
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    小鼠
    宿主
    • 60
    • 9
    • 2
    • 1
    克隆类型
    • 63
    • 9
    多克隆
    标记
    • 42
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRKACA antibody is conjugated to Cy3
    应用范围
    • 57
    • 31
    • 17
    • 13
    • 12
    • 12
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    小鼠
    预测反应
    Human,Rat
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Protein Kinase A regulatory subunit I alpha
    亚型
    IgG
    Top Product
    Discover our top product PRKACA Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    PRKACA (Protein Kinase A, alpha (PRKACA))
    别名
    PRKAR1 (PRKACA 产品)
    别名
    PKACA antibody, Calpha antibody, Cs-PKA antibody, PKCA1 antibody, PKA antibody, PKCD antibody, Pkaca antibody, zgc:158799 antibody, protein kinase cAMP-activated catalytic subunit alpha antibody, protein kinase, cAMP dependent, catalytic, alpha antibody, cAMP-dependent protein kinase catalytic subunit antibody, protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a antibody, PRKACA antibody, Prkaca antibody, kin-1 antibody, prkacaa antibody
    背景

    Synonyms: Protein Kinase A regulatory subunit I alpha, cAMP dependent protein kinase regulatory subunit alpha 1, cAMP dependent protein kinase regulatory subunit RIalpha, cAMP dependent protein kinase type I alpha regulatory chain, cAMP dependent protein kinase type I alpha regulatory subunit, CAR, CNC 1, CNC, CNC1, DKFZp779L0468, MGC17251, PKA RIA, PKR 1, PKR1, PPNAD 1, PPNAD1, PRKAR 1, PRKAR1, PRKAR1A, Protein kinase A type 1a regulatory subunitv Protein kinase cAMP dependent regulatory type I alpha, Tissue specic extinguisher 1, TSE 1, TSE1, KAP0_HUMAN.

    Background: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. This gene encodes one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids. Mutations in this gene cause Carney complex (CNC). This gene can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2. A nonconventional nuclear localization sequence (NLS) has been found for this protein which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40). Three alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008].

    基因ID
    5573
    途径
    NF-kappaB Signaling, Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, Lipid Metabolism, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
You are here:
客服