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Neuregulin 2 抗体 (Middle Region) (Biotin)

The 兔 多克隆 anti-Neuregulin 2 antibody is suitable to detect Neuregulin 2 in samples from 人, 大鼠 和 小鼠. It has been validated for WB, IHC 和 ELISA.
产品编号 ABIN8014548
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Neuregulin 2 抗体 (Middle Region) (Biotin) (ABIN8014548)

抗原

See all Neuregulin 2 (NRG2) 抗体
Neuregulin 2 (NRG2)

适用

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人, 大鼠, 小鼠

宿主

  • 46
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克隆类型

  • 47
  • 3
多克隆

标记

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This Neuregulin 2 antibody is conjugated to Biotin

应用范围

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  • 2
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 11
    • 8
    • 5
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    • 2
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    Middle Region

    原理

    Anti-NRG2 Antibody Biotin Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related rat sequence,and different from the related mouse sequence by one amino acid.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human NRG2, identical to the related rat sequence, and different from the related mouse sequence by one amino acid.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Neuregulin 2 (NRG2)

    别名

    NRG2

    背景

    Background: Neuregulin 2, also known as NRG2, DON1 or NTAK, is a protein that in humans is encoded by the NRG2 gene. Neuregulin 2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. The NRG2 gene is mapped to 5q31.2. Through interaction with the ErbB family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The human NRG2 gene contains 12 exons and the mouse Nrg2 gene contains 12 exons and spans about 180 kb. The NRG2 genomic structure is similar to that of neuregulin 1 (NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. In particular, the neuregulin-ERBB signaling pathways play crucial roles in regulating the proliferation and differentiation of Schwann cells, the myelin-forming cells in the peripheral nervous system.

    Gene Full Name: neuregulin 2

    Sequence Similarities: Belongs to the neuregulin family.

    基因ID

    9542

    UniProt

    O14511

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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