NOX1 抗体 (Middle Region) (APC)
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北京 101111
Quick Overview for NOX1 抗体 (Middle Region) (APC) (ABIN8013730)
抗原
See all NOX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-NADPH oxidase 1 NOX1 Antibody APC Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related mouse sequence by one amino acid.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of rat NOX1, different from the related mouse sequence by one amino acid.
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亚型
- IgG
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anti-NADPH Oxidase 1 (NOX1) antibody
NOX1 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (AA 235-488) antibodyNOX1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (Internal Region) antibodyVerified NOX1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (C-Term) antibodyNOX1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (AA 291-544) antibodyNOX1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (AA 418-564) antibodyNOX1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (C-Term) antibodyNOX1 适用: 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 斑马鱼, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (AA 425-515) antibodyNOX1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase 1 (NOX1) (AA 243-271) antibodyNOX1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB36700 unconjugated
anti-NADPH Oxidase 1 (NOX1) (AA 200-300) antibodyNOX1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- NOX1 (NADPH Oxidase 1 (NOX1))
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别名
- NOX1
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背景
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Background: NOX1 (NADPH OXIDASE 1), also known as NOH1, MOX1 or GP91-2, is an enzyme that in humans is encoded by the NOX1 gene. It is also a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. The NOX1 gene is mapped to Xq22.1. NOX1 was expressed in colon, prostate, uterus, and vascular smooth muscle, but not in peripheral blood leukocytes. The deduced 564-amino acid NOX1 protein, which is 58 % identical to CYBB, contains 6 membrane-spanning regions, conserved flavin and pyridine nucleotide-binding sites, and histidines possibly involved in heme ligation. Overexpression of MOX1 in NIH 3T3 cells increased superoxide generation and cell growth. Cells expressing MOX1 had a transformed appearance, showed anchorage-independent growth, and produced tumors in athymic mice. Disruption of either Nox1 or Nox2 significantly delayed progression of motor neuron disease in these mice. However, 50 % survival rates were enhanced significantly more by Nox2 deletion than Nox1 deletion.
Gene Full Name: NADPH oxidase 1
Sequence Similarities: Contains 1 FAD-binding FR-type domain.
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基因ID
- 114243
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UniProt
- Q9WV87
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones, Proton Transport
抗原
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