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NOX1 抗体

NOX1 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855720
发货至: 中国
  • 抗原 See all NOX1 抗体
    NOX1 (NADPH Oxidase 1 (NOX1))
    适用
    • 46
    • 9
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    • 2
    • 2
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    • 1
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    • 1
    • 1
    宿主
    • 45
    • 2
    • 1
    克隆类型
    • 47
    • 2
    多克隆
    标记
    • 29
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
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    This NOX1 antibody is un-conjugated
    应用范围
    • 34
    • 27
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    • 7
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Rabbit Polyclonal antibody to NOX1 (NADPH oxidase 1)
    NOX1 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human NOX1. The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: JC , BCL-1 , 293T , A431 , HeLa

    Validation: Orthogonal

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.19 mg/mL
    缓冲液
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Liang, Ma, Zhong, Dhar, Liu, Xu, Koyama, Nishio, Karin, Karin, Mccubbin, Zhang, Hu, Yang, Chen, Ganguly, Lan, Karin, Kisseleva, Brenner: "NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice." in: Gastroenterology, Vol. 156, Issue 4, pp. 1156-1172.e6, (2019) (PubMed).

    Sandrini, Ieraci, Amadio, Popoli, Tremoli, Barbieri: "Apocynin Prevents Abnormal Megakaryopoiesis and Platelet Activation Induced by Chronic Stress." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 9258937, (2018) (PubMed).

  • 抗原
    NOX1 (NADPH Oxidase 1 (NOX1))
    别名
    NADPH oxidase 1 (NOX1 产品)
    别名
    GP91-2 antibody, MOX1 antibody, NOH-1 antibody, NOH1 antibody, NOX1a antibody, NOX1alpha antibody, Nox-1 antibody, Nox1 antibody, NADPH oxidase 1 antibody, NOX1 antibody, Nox1 antibody, nox1 antibody
    背景
    Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Two transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Membrane, Multi-pass membrane protein
    分子量
    65 kDa
    基因ID
    27035
    UniProt
    Q9Y5S8
    途径
    Regulation of Systemic Arterial Blood Pressure by Hormones, Proton Transport
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