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MAP2K6 抗体 (N-Term)

The 兔 多克隆 anti-MAP2K6 antibody (ABIN8011234) specifically detects MAP2K6 in WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8011234
发货至: 中国
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Quick Overview for MAP2K6 抗体 (N-Term) (ABIN8011234)

抗原

See all MAP2K6 抗体
MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))

适用

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  • 2
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  • 1
人, 小鼠, 大鼠

宿主

  • 115
  • 8

克隆类型

  • 114
  • 9
多克隆

标记

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  • 1
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This MAP2K6 antibody is un-conjugated

应用范围

  • 87
  • 47
  • 27
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  • 14
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  • 3
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  • 1
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Western Blotting (WB)

质量等级

Carrier-free
  • 抗原表位

    • 18
    • 16
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    • 13
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    • 9
    • 7
    • 3
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    • 1
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    N-Term

    原理

    Anti-MEK6/MAP2K6 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related mouse sequence,different from the related rat sequence by one amino acid.

    产品特性

    Anti-MEK6/MAP2K6 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human MEK6, identical to the related mouse sequence and different from the related rat sequence by one amino acid.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))

    别名

    MAP2K6

    背景

    Background: MAP2K6 (Mitogen-activated protein kinase kinase 6), also known as MAP kinase kinase 6 (MAPKK 6) or MAPK/ERK kinase 6 is an enzyme that in humans is encoded by the MAP2K6 gene. It is located on chromosome 17. MAPKK 6 is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediatedsignal transduction pathway, this gene is involved in many cellular processes such as stress-induced cell cycle arrest, transcription activation and apoptosis.

    Gene Full Name: mitogen-activated protein kinase kinase 6

    Sequence Similarities: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.

    分子量

    22-24 kDa

    基因ID

    5608

    UniProt

    P52564

    途径

    MAPK Pathway, TLR signaling, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
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